Intrapulmonary Pharmacokinetics of GSK2251052 in Healthy Volunteers

The plasma and intrapulmonary pharmacokinetics (PK) of intravenous (i.v.) GSK2251052, a novel boron-containing antimicrobial, were evaluated in healthy adult subjects. Thirty subjects underwent bronchoscopy and timed bronchoalveolar lavage (BAL) either following a single dose (cohort 1) or after 5 t...

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Bibliographic Details
Main Authors: Tenero, David, Bowers, Gary, Rodvold, Keith A., Patel, Apurva, Kurtinecz, Milena, Dumont, Etienne, Tomayko, John, Patel, Parul
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697385/
https://ncbi.nlm.nih.gov/pubmed/23650164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02483-12
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