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Genomewide Screen for Modulators of Evolvability under Toxic Antibiotic Exposure

Antibiotic resistance is generally selected within a window of concentrations high enough to inhibit wild-type growth but low enough for new resistant mutants to emerge. We studied de novo evolution of resistance to ciprofloxacin in an Escherichia coli knockout library. Five null mutations had littl...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Méhi, Orsolya, Bogos, Balázs, Csörgő, Bálint, Pál, Csaba
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697378/
https://ncbi.nlm.nih.gov/pubmed/23669383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02454-12
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