Development of a Population Pharmacokinetic Model To Describe Azithromycin Whole-Blood and Plasma Concentrations over Time in Healthy Subjects

Azithromycin (AZI), a broad-spectrum antibiotic, accumulates in polymorphonuclear cells and peripheral blood mononuclear cells. The distribution of AZI in proinflammatory cells may be important to the anti-inflammatory properties. Previous studies have described plasma AZI pharmacokinetics. The obje...

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Bibliographische Detailangaben
Hauptverfasser: Pene Dumitrescu, T., Anic-Milic, T., Oreskovic, K., Padovan, J., Brouwer, K. L. R., Zuo, P., Schmith, V. D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Clinical Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697363/
https://ncbi.nlm.nih.gov/pubmed/23629714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02430-12
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