A Novel Method for Studying the Pharmacokinetics of [(14)C]Umeclidinium After Application to the Axilla or Palm of Healthy Male Subjects

Umeclidinium (UMEC), a long‐acting muscarinic antagonist approved for chronic obstructive pulmonary disease (COPD), was investigated for primary hyperhidrosis as topical therapy. This study evaluated the pharmacokinetics, safety, and tolerability of a single dose of [(14)C]UMEC applied to either uno...

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Publicado en:Clin Transl Sci
Autores principales: Pene Dumitrescu, T, Santos, LL, Hughes, SC, Pereira, AI, Young, GC, Hussey, E, Charlton, P, Baptiste‐Brown, S, Stuart, JS, Vincent, V, van Marle, SP, Schmith, VD
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351336/
https://ncbi.nlm.nih.gov/pubmed/27304394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12406
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