Loss and stabilization of amplified dihydrofolate reductase genes in mouse sarcoma S-180 cell lines.
We studied the loss and stabilization of dihydrofolate reductase genes in clones of a methotrexate-resistant murine S-180 cell line. These cells contained multiple copies of the dihydrofolate reductase gene which were associated with double minute chromosomes. The growth rate of these cells in the a...
Shranjeno v:
| izdano v: | Mol Cell Biol |
|---|---|
| Principais autores: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
1981
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369735/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7346713/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.1.12.1084-1093.1981 |
| Oznake: |
Brez oznak, prvi označite!
|