Preclinical Pharmacokinetics and Tissue Distribution of Long-Acting Nanoformulated Antiretroviral Therapy

Long-acting injectable nanoformulated antiretroviral therapy (nanoART) was developed with the explicit goal of improving medicine compliance and for drug targeting of viral tissue reservoirs. Prior nanoART studies completed in humanized virus-infected mice demonstrated sustained antiretroviral respo...

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Autores principales: Gautam, Nagsen, Roy, Upal, Balkundi, Shantanu, Puligujja, Pavan, Guo, Dongwei, Smith, Nathan, Liu, Xin-Ming, Lamberty, Benjamin, Morsey, Brenda, Fox, Howard S., McMillan, JoEllyn, Gendelman, Howard E., Alnouti, Yazen
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
Materias:
Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697338/
https://ncbi.nlm.nih.gov/pubmed/23612193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00267-13
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