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β-Amyloid Deposition and Functional Impairment in the Retina of the APPswe/PS1ΔE9 Transgenic Mouse Model of Alzheimer’s Disease

PURPOSE: To determine whether β-amyloid (Aβ) deposition affects the structure and function of the retina of the APPswe/PS1ΔE9 transgenic (tg) mouse model of Alzheimer’s disease. METHODS: Retinas from 12–19 month-old APPswe/PS1ΔE9 tg and age-matched non-transgenic (ntg) littermates were single or dou...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Perez, Sylvia E., Lumayag, Stephen, Kovacs, Beatrix, Mufson, Elliott J., Xu, Shunbin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697019/
https://ncbi.nlm.nih.gov/pubmed/18791173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2384
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