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β-Amyloid Deposition and Functional Impairment in the Retina of the APPswe/PS1ΔE9 Transgenic Mouse Model of Alzheimer’s Disease
PURPOSE: To determine whether β-amyloid (Aβ) deposition affects the structure and function of the retina of the APPswe/PS1ΔE9 transgenic (tg) mouse model of Alzheimer’s disease. METHODS: Retinas from 12–19 month-old APPswe/PS1ΔE9 tg and age-matched non-transgenic (ntg) littermates were single or dou...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3697019/ https://ncbi.nlm.nih.gov/pubmed/18791173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2384 |
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