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Amyloid beta deposition related retinal pigment epithelium cell impairment and subretinal microglia activation in aged APPswePS1 transgenic mice

AIM: To identify the pathological role of amyloid beta (Aβ) deposition in retinal degeneration, and explore Aβ deposition on the retinal pigment epithelium cells (RPE) layer and the associated structural and functional changes in Alzheimer's disease transgenic mice. METHODS: RPE changes in the...

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Dettagli Bibliografici
Pubblicato in:Int J Ophthalmol
Autori principali: Dong, Zhi-Zhang, Li, Juan, Gan, Yi-Feng, Sun, Xue-Rong, Leng, Yun-Xia, Ge, Jian
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Journal of Ophthalmology Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957024/
https://ncbi.nlm.nih.gov/pubmed/29862171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18240/ijo.2018.05.06
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