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Metabolic signatures of amyotrophic lateral sclerosis reveal insights into disease pathogenesis
Metabolic dysfunction is an important modulator of disease course in amyotrophic lateral sclerosis (ALS). We report here that a familial mouse model (transgenic mice over-expressing the G93A mutation of the Cu/Zn superoxide dismutase 1 gene) of ALS enters a progressive state of acidosis that is asso...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3696768/ https://ncbi.nlm.nih.gov/pubmed/23754387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308421110 |
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