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Glycosphingolipids are modulators of disease pathogenesis in amyotrophic lateral sclerosis

Recent genetic evidence suggests that aberrant glycosphingolipid metabolism plays an important role in several neuromuscular diseases including hereditary spastic paraplegia, hereditary sensory neuropathy type 1, and non-5q spinal muscular atrophy. Here, we investigated whether altered glycosphingol...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Dodge, James C., Treleaven, Christopher M., Pacheco, Joshua, Cooper, Samantha, Bao, Channa, Abraham, Marissa, Cromwell, Mandy, Sardi, S. Pablo, Chuang, Wei-Lien, Sidman, Richard L., Cheng, Seng H., Shihabuddin, Lamya S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491749/
https://ncbi.nlm.nih.gov/pubmed/26056266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508767112
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