Computational analysis of anti–HIV-1 antibody neutralization panel data to identify potential functional epitope residues

Advances in single-cell antibody cloning methods have led to the identification of a variety of broadly neutralizing anti–HIV-1 antibodies. We developed a computational tool (Antibody Database) to help identify critical residues on the HIV-1 envelope protein whose natural variation affects antibody...

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Detaylı Bibliyografya
Asıl Yazarlar: West, Anthony P., Scharf, Louise, Horwitz, Joshua, Klein, Florian, Nussenzweig, Michel C., Bjorkman, Pamela J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2013
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696754/
https://ncbi.nlm.nih.gov/pubmed/23754383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309215110
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