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Filter gate closure inhibits ion but not water transport through potassium channels
The selectivity filter of K(+) channels is conserved throughout all kingdoms of life. Carbonyl groups of highly conserved amino acids point toward the lumen to act as surrogates for the water molecules of K(+) hydration. Ion conductivity is abrogated if some of these carbonyl groups flip out of the...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3696751/ https://ncbi.nlm.nih.gov/pubmed/23754382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304714110 |
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