Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Phosphorylation by Protein Kinase Cδ (PKCδ) Inhibits Mitochondria Elimination by Lysosomal-like Structures following Ischemia and Reoxygenation-induced Injury

After cardiac ischemia and reperfusion or reoxygenation (I/R), damaged mitochondria propagate tissue injury by promoting cell death. One possible mechanism to protect from I/R-induced injury is the elimination of damaged mitochondria by mitophagy. Here we identify new molecular events that lead to m...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Yogalingam, Gouri, Hwang, Sunhee, Ferreira, Julio C. B., Mochly-Rosen, Daria
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2013
Ämnen:
Cell Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696670/
https://ncbi.nlm.nih.gov/pubmed/23653351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.466870
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