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Mutation signature of adenoid cystic carcinoma: evidence for transcriptional and epigenetic reprogramming

Adenoid cystic carcinoma (ACC), a relatively rare malignancy usually of salivary gland origin, has a signature v-myb avian myeloblastosis viral oncogene homolog–nuclear factor I/B (MYB-NFIB) gene fusion that activates MYB transcriptional regulatory activity. A new study in this issue by Stephens et...

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Hlavní autoři: Frierson, Henry F., Moskaluk, Christopher A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696562/
https://ncbi.nlm.nih.gov/pubmed/23778135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69070
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