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Mutation signature of adenoid cystic carcinoma: evidence for transcriptional and epigenetic reprogramming
Adenoid cystic carcinoma (ACC), a relatively rare malignancy usually of salivary gland origin, has a signature v-myb avian myeloblastosis viral oncogene homolog–nuclear factor I/B (MYB-NFIB) gene fusion that activates MYB transcriptional regulatory activity. A new study in this issue by Stephens et...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3696562/ https://ncbi.nlm.nih.gov/pubmed/23778135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69070 |
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