Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is the commonest childhood malignancy and is characterized by recurring structural genetic alterations. Previous studies of DNA methylation suggest epigenetic alterations may also be important, but an integrated genome-wide analysis of genetic and epigenetic altera...

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Detalhes bibliográficos
Main Authors: Figueroa, Maria E., Chen, Shann-Ching, Andersson, Anna K., Phillips, Letha A., Li, Yushan, Sotzen, Jason, Kundu, Mondira, Downing, James R., Melnick, Ari, Mullighan, Charles G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696550/
https://ncbi.nlm.nih.gov/pubmed/23921123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66203
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