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Molecular and behavioral pharmacology of two novel orally-active 5HT2 modulators: potential utility as antipsychotic medications

BACKGROUND: Desired serotonin 5HT2 receptor pharmacology for treatment of psychoses is 5HT2A antagonism and/or 5HT2C agonism. No selective 5HT2A antagonist has been approved for psychosis and the only approved 5HT2C agonist (for obesity) also activates 5HT2A and 5HT2B receptors, which can lead to cl...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Morgan, Drake, Kondabolu, Krishnakanth, Kuipers, Allison, Sakhuja, Rajeev, Robertson, Kimberly L., Rowland, Neil E., Booth, Raymond G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696402/
https://ncbi.nlm.nih.gov/pubmed/23665356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.04.051
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