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The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA.

The translocation (6;9) is associated with a specific subtype of acute myeloid leukemia (AML). Previously, it was found that breakpoints on chromosome 9 are clustered in one of the introns of a large gene named Cain (can). cDNA probes derived from the 3' part of can detect an aberrant, leukemia...

詳細記述

保存先:
書誌詳細
出版年:Mol Cell Biol
主要な著者: von Lindern, M, Fornerod, M, van Baal, S, Jaegle, M, de Wit, T, Buijs, A, Grosveld, G
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 1992
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369612/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1549122/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.4.1687
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