The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA.

The translocation (6;9) is associated with a specific subtype of acute myeloid leukemia (AML). Previously, it was found that breakpoints on chromosome 9 are clustered in one of the introns of a large gene named Cain (can). cDNA probes derived from the 3' part of can detect an aberrant, leukemia-spec...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	von Lindern, M, Fornerod, M, van Baal, S, Jaegle, M, de Wit, T, Buijs, A, Grosveld, G
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1992
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369612/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1549122/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.4.1687-1697.1992
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