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The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA.

The translocation (6;9) is associated with a specific subtype of acute myeloid leukemia (AML). Previously, it was found that breakpoints on chromosome 9 are clustered in one of the introns of a large gene named Cain (can). cDNA probes derived from the 3' part of can detect an aberrant, leukemia...

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Bibliografski detalji
Glavni autori: von Lindern, M, Fornerod, M, van Baal, S, Jaegle, M, de Wit, T, Buijs, A, Grosveld, G
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC369612/
https://ncbi.nlm.nih.gov/pubmed/1549122
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