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Bim Mediates the Elimination of Functionally Unfit Th1 Responders from the Memory Pool
Selective clonal deletion in the CD4(+) T cell compartment during the transition from effector to memory is accompanied by enhanced expression of the pro-apoptotic Bcl-2 family member Bim. Here, we show that Bim deficiency enables the survival of poorly functional Th1 responders that are normally el...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3696111/ https://ncbi.nlm.nih.gov/pubmed/23840678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067363 |
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