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Bim Mediates the Elimination of Functionally Unfit Th1 Responders from the Memory Pool

Selective clonal deletion in the CD4(+) T cell compartment during the transition from effector to memory is accompanied by enhanced expression of the pro-apoptotic Bcl-2 family member Bim. Here, we show that Bim deficiency enables the survival of poorly functional Th1 responders that are normally el...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Jay, David C., Mitchell, Diana M., Williams, Matthew A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696111/
https://ncbi.nlm.nih.gov/pubmed/23840678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067363
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