Hsp70 Oligomerization Is Mediated by an Interaction between the Interdomain Linker and the Substrate-Binding Domain

Oligomerization in the heat shock protein (Hsp) 70 family has been extensively documented both in vitro and in vivo, although the mechanism, the identity of the specific protein regions involved and the physiological relevance of this process are still unclear. We have studied the oligomeric propert...

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Autori principali: Aprile, Francesco A., Dhulesia, Anne, Stengel, Florian, Roodveldt, Cintia, Benesch, Justin L. P., Tortora, Paolo, Robinson, Carol V., Salvatella, Xavier, Dobson, Christopher M., Cremades, Nunilo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696110/
https://ncbi.nlm.nih.gov/pubmed/23840795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067961
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