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Human gamma- to beta-globin gene switching using a mini construct in transgenic mice.

The developmental regulation of the human globin genes involves a key switch from fetal (gamma-) to adult (beta-) globin gene expression. It is possible to study the mechanism of this switch by expressing the human globin genes in transgenic mice. Previous work has shown that high-level expression o...

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Dades bibliogràfiques
Publicat a:Mol Cell Biol
Autors principals: Lloyd, J A, Krakowsky, J M, Crable, S C, Lingrel, J B
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369598/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1549112/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.4.1561-1567.1992
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