Human gamma- to beta-globin gene switching using a mini construct in transgenic mice.
The developmental regulation of the human globin genes involves a key switch from fetal (gamma-) to adult (beta-) globin gene expression. It is possible to study the mechanism of this switch by expressing the human globin genes in transgenic mice. Previous work has shown that high-level expression o...
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| Publicat a: | Mol Cell Biol |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1992
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369598/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1549112/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.4.1561-1567.1992 |
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