Human gamma- to beta-globin gene switching using a mini construct in transgenic mice.

The developmental regulation of the human globin genes involves a key switch from fetal (gamma-) to adult (beta-) globin gene expression. It is possible to study the mechanism of this switch by expressing the human globin genes in transgenic mice. Previous work has shown that high-level expression o...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Lloyd, J A, Krakowsky, J M, Crable, S C, Lingrel, J B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369598/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1549112/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.4.1561-1567.1992
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