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A mathematical model of the unfolded protein stress response reveals the decision mechanism for recovery, adaptation and apoptosis
BACKGROUND: The unfolded protein response (UPR) is a major signalling cascade acting in the quality control of protein folding in the endoplasmic reticulum (ER). The cascade is known to play an accessory role in a range of genetic and environmental disorders including neurodegenerative and cardiovas...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3695880/ https://ncbi.nlm.nih.gov/pubmed/23433609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-16 |
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