Stable tumor vessel normalization with pO(2) increase and endothelial PTEN activation by inositol trispyrophosphate brings novel tumor treatment

Tumor hypoxia is a characteristic of cancer cell growth and invasion, promoting angiogenesis, which facilitates metastasis. Oxygen delivery remains impaired because tumor vessels are anarchic and leaky, contributing to tumor cell dissemination. Counteracting hypoxia by normalizing tumor vessels in o...

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Bibliografische gegevens
Hoofdauteurs: Kieda, Claudine, El Hafny-Rahbi, Bouchra, Collet, Guillaume, Lamerant-Fayel, Nathalie, Grillon, Catherine, Guichard, Alan, Dulak, Jozef, Jozkowicz, Alicja, Kotlinowski, Jerzy, Fylaktakidou, Konstantina C., Vidal, Aurélien, Auzeloux, Philippe, Miot-Noirault, Elisabeth, Beloeil, Jean-Claude, Lehn, Jean-Marie, Nicolau, Claude
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Berlin Heidelberg 2013
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695680/
https://ncbi.nlm.nih.gov/pubmed/23471434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-013-0992-6
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