Stable tumor vessel normalization with pO(2) increase and endothelial PTEN activation by inositol trispyrophosphate brings novel tumor treatment

Tumor hypoxia is a characteristic of cancer cell growth and invasion, promoting angiogenesis, which facilitates metastasis. Oxygen delivery remains impaired because tumor vessels are anarchic and leaky, contributing to tumor cell dissemination. Counteracting hypoxia by normalizing tumor vessels in o...

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Detalles Bibliográficos
Autores principales: Kieda, Claudine, El Hafny-Rahbi, Bouchra, Collet, Guillaume, Lamerant-Fayel, Nathalie, Grillon, Catherine, Guichard, Alan, Dulak, Jozef, Jozkowicz, Alicja, Kotlinowski, Jerzy, Fylaktakidou, Konstantina C., Vidal, Aurélien, Auzeloux, Philippe, Miot-Noirault, Elisabeth, Beloeil, Jean-Claude, Lehn, Jean-Marie, Nicolau, Claude
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Berlin Heidelberg 2013
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695680/
https://ncbi.nlm.nih.gov/pubmed/23471434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-013-0992-6
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