Synthesis of (18)O-labeled RNA for application to kinetic studies and imaging

Radioisotopes and fluorescent compounds are frequently used for RNA labeling but are unsuitable for clinical studies of RNA drugs because of the risk from radiation exposure or the nonequivalence arising from covalently attached fluorophores. Here, we report a practical phosphoramidite solid-phase s...

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Detalhes bibliográficos
Main Authors: Hamasaki, Tomohiro, Matsumoto, Takahiro, Sakamoto, Naoya, Shimahara, Akiko, Kato, Shiori, Yoshitake, Ayumi, Utsunomiya, Ayumi, Yurimoto, Hisayoshi, Gabazza, Esteban C., Ohgi, Tadaaki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695515/
https://ncbi.nlm.nih.gov/pubmed/23632164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt344
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