Efficacy of a Novel Class of RNA Interference Therapeutic Agents

RNA interference (RNAi) is being widely used in functional gene research and is an important tool for drug discovery. However, canonical double-stranded short interfering RNAs are unstable and induce undesirable adverse effects, and thus there is no currently RNAi-based therapy in the clinic. We hav...

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Detalhes bibliográficos
Main Authors: Hamasaki, Tomohiro, Suzuki, Hiroshi, Shirohzu, Hisao, Matsumoto, Takahiro, D'Alessandro-Gabazza, Corina N., Gil-Bernabe, Paloma, Boveda-Ruiz, Daniel, Naito, Masahiro, Kobayashi, Tetsu, Toda, Masaaki, Mizutani, Takayuki, Taguchi, Osamu, Morser, John, Eguchi, Yutaka, Kuroda, Masahiko, Ochiya, Takahiro, Hayashi, Hirotake, Gabazza, Esteban C., Ohgi, Tadaaki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419724/
https://ncbi.nlm.nih.gov/pubmed/22916145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042655
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