MCARD-Mediated Gene Transfer of GRK2 Inhibitor in Ovine Model of Acute Myocardial Infarction

β-adrenergic receptor (βAR) dysfunction in acute myocardial infarction (MI) is associated with elevated levels of the G protein-coupled receptor kinase-2 (GRK2), which plays a key role in heart failure progression. Inhibition of GRK2 via expression of a peptide βARKct transferred by molecular cardia...

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Detalhes bibliográficos
Main Authors: Swain, JaBaris D., Fargnoli, Anthony S., Katz, Michael G., Tomasulo, Catherine E., Sumaroka, Marina, Richardville, Kyle C., Koch, Walter J., Rabinowitz, Joseph E., Bridges, Charles R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695486/
https://ncbi.nlm.nih.gov/pubmed/23208013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-012-9418-z
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