Megakaryocytes promote murine osteoblastic HSC niche expansion and stem cell engraftment after radioablative conditioning

Successful hematopoietic stem cell (HSC) transplantation requires donor HSC engraftment within specialized bone marrow microenvironments known as HSC niches. We have previously reported a profound remodeling of the endosteal osteoblastic HSC niche after total body irradiation (TBI), defined as reloc...

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Sonraí Bibleagrafaíochta
Main Authors: Olson, Timothy S., Caselli, Anna, Otsuru, Satoru, Hofmann, Ted J., Williams, Richard, Paolucci, Paolo, Dominici, Massimo, Horwitz, Edwin M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Hematology 2013
Ábhair:
Transplantation
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695366/
https://ncbi.nlm.nih.gov/pubmed/23667055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-10-463414
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