Restoration and reversible expansion of the osteoblastic hematopoietic stem cell niche after marrow radioablation

Adequate recovery of hematopoietic stem cell (HSC) niches after cytotoxic conditioning regimens is essential to successful bone marrow transplantation. Yet, very little is known about the mechanisms that drive the restoration of these niches after bone marrow injury. Here we describe a profound disr...

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Main Authors: Dominici, Massimo, Rasini, Valeria, Bussolari, Rita, Chen, Xiaohua, Hofmann, Ted J., Spano, Carlotta, Bernabei, Daniela, Veronesi, Elena, Bertoni, Filippo, Paolucci, Paolo, Conte, PierFranco, Horwitz, Edwin M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2009
Assuntos:
Transplantation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745851/
https://ncbi.nlm.nih.gov/pubmed/19433859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-10-183459
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