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Megakaryocytes promote murine osteoblastic HSC niche expansion and stem cell engraftment after radioablative conditioning

Successful hematopoietic stem cell (HSC) transplantation requires donor HSC engraftment within specialized bone marrow microenvironments known as HSC niches. We have previously reported a profound remodeling of the endosteal osteoblastic HSC niche after total body irradiation (TBI), defined as reloc...

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Detalhes bibliográficos
Main Authors: Olson, Timothy S., Caselli, Anna, Otsuru, Satoru, Hofmann, Ted J., Williams, Richard, Paolucci, Paolo, Dominici, Massimo, Horwitz, Edwin M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695366/
https://ncbi.nlm.nih.gov/pubmed/23667055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-10-463414
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