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Dopamine Release Suppression Dependent on an Increase of Intracellular Ca(2+) Contributed to Rotenone-induced Neurotoxicity in PC12 Cells

Rotenone is an inhibitor of mitochondrial complex I that produces a model of Parkinson’s disease (PD), in which neurons undergo dopamine release dysfunction and other features. In neurons, exocytosis is one of the processes associated with dopamine release and is dependent on Ca(2+) dynamic changes...

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Bibliografski detalji
Glavni autori: Sai, Yan, Chen, Junfeng, Ye, Feng, Zhao, Yuanpeng, Zou, Zhongmin, Cao, Jia, Dong, Zhaojun
Format: Artigo
Jezik:Inglês
Izdano: Japanese Society of Toxicologic Pathology 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695337/
https://ncbi.nlm.nih.gov/pubmed/23914057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.26.149
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