Cooperative Synthesis of Ultra Long-Chain Fatty Acid and Ceramide during Keratinocyte Differentiation

The lipid lamellae in the stratum corneum is important for the epidermal permeability barrier. The lipid lamellae component ceramide (CER), comprising an ultra long-chain (ULC) fatty acid (FA) of ≥26 carbons (ULC CER), plays an essential role in barrier formation. ULC acyl-CoAs, produced by the FA e...

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Detalhes bibliográficos
Main Authors: Mizutani, Yukiko, Sun, Hui, Ohno, Yusuke, Sassa, Takayuki, Wakashima, Takeshi, Obara, Mari, Yuyama, Kohei, Kihara, Akio, Igarashi, Yasuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694974/
https://ncbi.nlm.nih.gov/pubmed/23826266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067317
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