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Negative Regulation of TLR Inflammatory Signaling by the SUMO-deconjugating Enzyme SENP6
The signaling of Toll-like receptors (TLRs) induces host defense against microbial invasion. Protein posttranslational modifications dynamically shape the strength and duration of the signaling pathways. It is intriguing to explore whether de-SUMOylation could modulate the TLR signaling. Here we ide...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3694847/ https://ncbi.nlm.nih.gov/pubmed/23825957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003480 |
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