Negative Regulation of TLR Inflammatory Signaling by the SUMO-deconjugating Enzyme SENP6

The signaling of Toll-like receptors (TLRs) induces host defense against microbial invasion. Protein posttranslational modifications dynamically shape the strength and duration of the signaling pathways. It is intriguing to explore whether de-SUMOylation could modulate the TLR signaling. Here we ide...

Full description

Saved in:
Bibliographic Details
Main Authors: Liu, Xing, Chen, Wei, Wang, Qiang, Li, Li, Wang, Chen
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694847/
https://ncbi.nlm.nih.gov/pubmed/23825957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003480
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items