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DNA Methylation Restricts Lineage-specific Functions of Transcription Factor Gata4 during Embryonic Stem Cell Differentiation

DNA methylation changes dynamically during development and is essential for embryogenesis in mammals. However, how DNA methylation affects developmental gene expression and cell differentiation remains elusive. During embryogenesis, many key transcription factors are used repeatedly, triggering diff...

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書誌詳細
主要な著者: Oda, Masaaki, Kumaki, Yuichi, Shigeta, Masaki, Jakt, Lars Martin, Matsuoka, Chisa, Yamagiwa, Akiko, Niwa, Hitoshi, Okano, Masaki
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694845/
https://ncbi.nlm.nih.gov/pubmed/23825962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003574
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