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DNA methylation regulates long-range gene silencing of an X-linked homeobox gene cluster in a lineage-specific manner

DNA methylation is a major epigenetic mechanism that has been suggested to control developmental gene regulation during embryogenesis, but its regulatory mechanisms remain unclear. In this report, we show that CpG islands associated with the X-linked homeobox gene cluster Rhox, which is highly expre...

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Detalhes bibliográficos
Main Authors: Oda, Masaaki, Yamagiwa, Akiko, Yamamoto, Shinji, Nakayama, Takao, Tsumura, Akiko, Sasaki, Hiroshi, Nakao, Kazuki, Li, En, Okano, Masaki
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698446/
https://ncbi.nlm.nih.gov/pubmed/17182866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1470906
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