Rapamycin sensitivity in Saccharomyces cerevisiae is mediated by a peptidyl-prolyl cis-trans isomerase related to human FK506-binding protein.

Rapamycin is a macrolide antifungal agent with structural similarity to FK506. It exhibits potent immunosuppressive properties analogous to those of both FK506 and cyclosporin A (CsA). Unlike FK506 and CsA, however, rapamycin does not inhibit the transcription of early T-cell activation genes, inclu...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Koltin, Y, Faucette, L, Bergsma, D J, Levy, M A, Cafferkey, R, Koser, P L, Johnson, R K, Livi, G P
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1991
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC369480/
https://ncbi.nlm.nih.gov/pubmed/1996117
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi