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Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals
The mammalian circadian clock involves a transcriptional feedback loop in which CLOCK and BMAL1 activate the Period and Cryptochrome genes, which then feedback and repress their own transcription. We have interrogated the transcriptional architecture of the circadian transcriptional regulatory loop...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3694775/ https://ncbi.nlm.nih.gov/pubmed/22936566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1226339 |
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