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Molecular components of the circadian clock in mammals
The circadian clock mechanism in animals involves a transcriptional feedback loop in which the bHLH-PAS proteins CLOCK and BMAL1 form a transcriptional activator complex to activate the transcription of the Period and Cryptochrome genes, which in turn feed back to repress their own transcription. In...
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| Publicado no: | Diabetes Obes Metab |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4560116/ https://ncbi.nlm.nih.gov/pubmed/26332962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.12514 |
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