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Molecular components of the circadian clock in mammals

The circadian clock mechanism in animals involves a transcriptional feedback loop in which the bHLH-PAS proteins CLOCK and BMAL1 form a transcriptional activator complex to activate the transcription of the Period and Cryptochrome genes, which in turn feed back to repress their own transcription. In...

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Détails bibliographiques
Publié dans:Diabetes Obes Metab
Auteur principal: Takahashi, Joseph S.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560116/
https://ncbi.nlm.nih.gov/pubmed/26332962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.12514
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