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Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals

The mammalian circadian clock involves a transcriptional feedback loop in which CLOCK and BMAL1 activate the Period and Cryptochrome genes, which then feedback and repress their own transcription. We have interrogated the transcriptional architecture of the circadian transcriptional regulatory loop...

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Detalhes bibliográficos
Main Authors: Koike, Nobuya, Yoo, Seung-Hee, Huang, Hung-Chung, Kumar, Vivek, Lee, Choogon, Kim, Tae-Kyung, Takahashi, Joseph S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694775/
https://ncbi.nlm.nih.gov/pubmed/22936566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1226339
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