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Learning subgroup-specific regulatory interactions and regulator independence with PARADIGM
High-dimensional ‘-omics’ profiling provides a detailed molecular view of individual cancers; however, understanding the mechanisms by which tumors evade cellular defenses requires deep knowledge of the underlying cellular pathways within each cancer sample. We extended the PARADIGM algorithm (Vaske...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2013
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3694636/ https://ncbi.nlm.nih.gov/pubmed/23813010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt229 |
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