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ZFN, TALEN and CRISPR/Cas-based methods for genome engineering

Zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs) comprise a powerful class of tools that are redefining the boundaries of biological research. These chimeric nucleases are composed of programmable, sequence-specific DNA-binding modules linked to a non-specifi...

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Autors principals: Gaj, Thomas, Gersbach, Charles A., Barbas, Carlos F.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694601/
https://ncbi.nlm.nih.gov/pubmed/23664777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibtech.2013.04.004
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