Matrix metalloproteinases inhibition promotes the polyfunctionality of human natural killer cells in therapeutic antibody-based anti-tumour immunotherapy

Activation of human natural killer (NK) cells is associated with the cleavage of CD16 from the cell surface, a process mediated by matrix metalloproteinases (MMPs). In this report, we examined whether inhibition of MMPs would lead to improved NK cell antibody-dependent cell-mediated cytotoxicity (AD...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhou, Q, Gil-Krzewska, A, Peruzzi, G, Borrego, F
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2013
Konular:
Translational Studies
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694543/
https://ncbi.nlm.nih.gov/pubmed/23607800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12095
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