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Membrane-Type 6 Matrix Metalloproteinase, MT6-MMP, Regulates the Activation-Induced Down-Modulation of CD16 in Human Primary NK Cells
CD16 (Fc RIIIa), the low affinity receptor for IgG, expressed by the majority of human natural killer (NK) cells, is a potent activating receptor that facilitates antibody-dependent cell-mediated cytotoxicity (ADCC). ADCC dysfunction has been linked to cancer progression and poor prognosis for chron...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3745217/ https://ncbi.nlm.nih.gov/pubmed/23851692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300313 |
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