Membrane-Type 6 Matrix Metalloproteinase, MT6-MMP, Regulates the Activation-Induced Down-Modulation of CD16 in Human Primary NK Cells

CD16 (Fc RIIIa), the low affinity receptor for IgG, expressed by the majority of human natural killer (NK) cells, is a potent activating receptor that facilitates antibody-dependent cell-mediated cytotoxicity (ADCC). ADCC dysfunction has been linked to cancer progression and poor prognosis for chron...

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Detaylı Bibliyografya
Asıl Yazarlar: Peruzzi, Giovanna, Femnou, Laurette, Gil-Krzewska, Aleksandra, Borrego, Francisco, Weck, Jennifer, Krzewski, Konrad, Coligan, John E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745217/
https://ncbi.nlm.nih.gov/pubmed/23851692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300313
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