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Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cells.

We have introduced a 4-bp insertion into the hypoxanthine phosphoribosyltransferase (HPRT) gene of a mouse embryonic stem (ES) cell line by using an "in-out" targeting procedure. During the in step, a homologous integration reaction, we targeted a correcting plasmid to a partially deleted...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Valancius, V, Smithies, O
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1991
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC369413/
https://ncbi.nlm.nih.gov/pubmed/1996101
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